Recombinant CD30 Ligand Protein (Gln 63-Asp 234) [Fc] (VAng-1256Lsx)
Human CD30 Ligand, Mouse IgG2a Fc Tag, is expressed in HEK 293 cells. (Uniprot ID: P32971-1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD30 Ligand
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
TNFSF8 (TNF Superfamily Member 8) is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas.
Alternative Names
CD30-L, CD153, TNFSF8, CD30L, CD30LG, CD153 antigen, CD30 antigen ligand, CD30 Ligand
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
