Recombinant CD3E&CD3D Heterodimer Protein (Asp 23-Asp 126 (CD3E) & Phe 22-Ala 105 (CD3D)) [Fc] (VAng-1289Lsx)
Human CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc, is expressed in HEK 293 cells. (Uniprot ID: P07766-1 (CD3E) & P04234-1 (CD3D))
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD3E
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD3E is a protein encoded by CD3E gene. The CD3-epsilon polypeptide, together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Alternative Names
CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
