Recombinant CD3E&CD3D Heterodimer Protein (Asp 23-Asp 126 (CD3E) & Phe 22-Ala 105 (CD3D)) [Fc] [His] [Flag] (VAng-1290Lsx)

Human CD3E&CD3D Heterodimer Protein, Fc,His Tag&Fc,Flag Tag, is expressed in HEK 293 cells. (Uniprot ID: P07766-1 (CD3E) & P04234-1 (CD3D))

Datasheet

Specifications

Source

HEK293 Cells.

Target

CD3E

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CD3E is a protein encoded by CD3E gene. The CD3-epsilon polypeptide, together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Alternative Names

CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon