Recombinant CD3E&CD3G Heterodimer Protein (Asp 23-Asp 126 (CD3E) & Gln 23-Ser 116 (CD3G)) [Fc] (VAng-1294Lsx)

Cynomolgus CD3E&CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag, is expressed in HEK 293 cells. (Uniprot ID: NP_000724.1 (CD3E) & AAI13831 (CD3G))

Datasheet

Specifications

Source

HEK293 Cells.

Target

CD3E

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CD3E is a protein encoded by CD3E gene. The CD3-epsilon polypeptide, together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Alternative Names

CD3 epsilon & CD3 gamma, CD3E & CD3G