Recombinant CD3E Protein (Met1-Asp126) [His] (VAng-Cr3749)
Recombinant CD3E Protein (Met1-Asp126) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 18 kDa. (Uniprot ID: P07766)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Introduction
CD3E is a protein encoded by CD3E gene. The CD3-epsilon polypeptide, together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
Alternative Names
CD3E; T3E
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