Recombinant CD46 Protein (Cys 35-Asp 328) [His] (VAng-1322Lsx)
Human CD46, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH30594.1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD46
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD46 is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Alternative Names
CD46, AHUS2, MCP, MIC10, TLX, TRA2.10
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