Recombinant CD52 Protein (Gly 25-Ser 36) [Fc] [Avi] (VAng-1346Lsx)

Biotinylated Human CD52, Fc tag and Avi tag, is expressed in HEK 293 cells. (Uniprot ID: P31358-1)

Specifications
Source
HEK293 Cells.
Target
CD52
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Tris with Glycine, Arginine and NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD52 is a glycoprotein that in humans is encoded by CD52 gene. CD52 is present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It also is found on monocytes and dendritic cells. Further, it is found within the male genital tract and is present on the surface of mature sperm cells. CD52 is a peptide of 12 amino acids, anchored to glycosylphosphatidylinositol (GPI). Since it is highly negatively charged and present on sperm cells and lymphocytes, it has been conjectured that its function is anti-adhesion, allowing cells to freely move around.
Alternative Names
CDW52, HE5, CD52, CAMPATH-1 antigen
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