Recombinant CD68 Protein (Asn 22-Ser 319) [Fc] (VAng-1354Lsx)
Human CD68, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH15557)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD68
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD68 is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages.
Alternative Names
CD68, Macrosialin, Gp110, SCARD1
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