Recombinant CD74 Protein (Gln 73-Met 232) [His] (VAng-1359Lsx)
Human CD74 (DHLAG), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_004346.1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD74
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD74 associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta).
Alternative Names
CD74, DHLAG, HLADG, II, Ia-GAMMA, p33, CLIP, INVG34
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