Recombinant CD80 Protein (Met1-Asn242) [His] (VAng-Cr3820)
Recombinant CD80 Protein (Met1-Asn242) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 45 kDa. (Uniprot ID: P33681)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Introduction
CD80 is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Alternative Names
B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7; CD80 molecule
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