Cynomolgus / Rhesus macaque CD80 Protein (Val 35-Asn 242) [His] (VAng-1365Lsx)
Cynomolgus / Rhesus macaque CD80 (B7-1), His tag, is expressed in HEK 293 cells. (Uniprot ID: G7NXN7)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CD80
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD80 is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Alternative Names
CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Related Product
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