Recombinant CD96 Protein (Met1-Met519) [His] (VAng-Cr3856)

Recombinant CD96 Protein (Met1-Met519) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 120-130 kDa. (Uniprot ID: P40200)

Datasheet

Specifications

Source

Mammalian cells

Target

CD96

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

CD96 is a receptor expressed on T cells and NK cells, and shares sequence similarity with CD226. The protein encoded by CD96 gene belongs to the immunoglobulin superfamily. It is a type I membrane protein. The protein may play a role in the adhesion of activated T and NK cells to their target cells during the late phase of the immune response. It may also function in antigen presentation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. CD96 is a transmembrane glycoprotein that has three extracellular immunoglobulin-like domains and is expressed by all resting human and mouse NK cells. CD96 main ligand is CD155. CD 96 has approximately 20% homology with CD226 and competed for binding to CD155 with CD226.

Alternative Names

T-Cell Surface Protein Tactile; TACTILE