Recombinant CEACAM-5 Protein (Lys 35-Ala 685) (VAng-1394Lsx)

Human CEACAM-5 (CD66e) is expressed in HEK 293 cells. (Uniprot ID: P06731)

Specifications
Source
HEK293 Cells.
Target
CEACAM5
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CEACAM5 is a member of the carcinoembryonic antigen (CEA) family. It plays a role in cell adhesion, intracellular signaling and tumor progression. It mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules. The protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. Its gene is present in a CEA family on chromosome 19. Alternative splicing results in multiple transcript variants.
Alternative Names
CEACAM-5, CD66e, CEA, Meconium antigen 100
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