Recombinant Chlorocebus aethiops Cathepsin L Protein (aa 18-334) (Mammalian Cells) (VAng-4219Lsx)

Recombinant Chlorocebus aethiops Cathepsin L (CTSL1) protein, expressed in Mammalian Cells. (Uniprot ID: Q9GKL8)

Datasheet

Specifications

Source

Mammalian Cells

Target

Cathepsin L

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

PBS, pH 7.4.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CTSL (Cathepsin L) is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor.

Alternative Names

CTSL1, MEP, CATL, CTSL