Recombinant CNTF R alpha Protein (Gln 23-Pro 346) [His] (VAng-1409Lsx)
Human CNTF R alpha, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH01492)
Datasheet
Specifications
Source
HEK293 Cells.
Target
CNTF R alpha
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CNTFR (Ciliary Neurotrophic Factor Receptor) is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders.
Alternative Names
CNTFR, CNTF R alpha
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