Recombinant Cynomolgus CD80 Protein (aa 1-242) [Fc] (VAng-Cr3933)
Recombinant Cynomolgus CD80 Protein (Met 1-Asn242) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 50.9 kDa. (Accession ID: AAC31555.1)
Datasheet
Specifications
Source
Cynomolgus
Target
CD80
Type
Tumor Antigens
Applications
ELISA.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD80 is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
Alternative Names
B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7; CD80 molecule
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
