Recombinant ENPP-2 Protein (Asp 49-Ile 863) [His] (VAng-1488Lsx)
Human ENPP-2 (EMMPRIN), His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_001035181)
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 150 mM NaCl, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 2) functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas.
Alternative Names
ENPP2, E-NPP 2, Autotaxin, LysoPLD, ATX, PDNP2, ATX-X, NPP2, PD-IALPHA
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