Recombinant EphB4 Protein (Glu 17-Ala 539) [His] (VAng-1499Lsx)
Human EphB4, His tag, is expressed in HEK 293 cells. (Uniprot ID: NP_004435.3)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 97% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. Diseases associated with EPHB4 include Capillary Malformation-Arteriovenous Malformation 2 and Lymphatic Malformation 7.
Alternative Names
EphB4, HTK, MYK1, TYRO11
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