Recombinant Erythropoietin R Protein (Ala 25-Cys 241) [Fc] (VAng-1517Lsx)
Human Erythropoietin R (EPOR), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAI12154)
Datasheet
Specifications
Source
HEK293 Cells.
Target
Erythropoietin R
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
50 mM Tris, 100 mM Glycine, pH 7.5.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
EPOR (Erythropoietin Receptor) is the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.
Alternative Names
EPOR
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