Recombinant Fas Ligand Protein (Pro 134-Leu 281) [His] (VAng-1531Lsx)
Human Fas Ligand (TNFSF6), Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH17502.1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
Fas Ligand
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
FASLG (Fas Ligand) is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE).
Alternative Names
FASLG, ALPS1B, APT1LG1, CD178, CD95L, FASL, TNFSF6
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
