Recombinant Furin Protein (Gln 25-Gly 577) [His] (VAng-1593Lsx)
Human Furin, His tag, is expressed in HEK 293 cells. (Uniprot ID: AAH12181.1)
Datasheet
Specifications
Source
HEK293 Cells.
Target
Furin
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
20 mM Tris, 150 mM NaCl, 1 mM CaCl₂, 0.01% Birj-35, pH 9.0.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
FURIN (Furin, Paired Basic Amino Acid Cleaving Enzyme) a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired.
Alternative Names
FURIN, FUR, PACE, PCSK3, SPC1
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