Recombinant HCV Core, NS3, NS4 and NS5 Protein, immunodominant regions (VAng-0508Lsx)
Recombinant Hepatitis C virus antigen, contains the HCV core (aa 11-53), NS3 (aa 1210-1450, 1337-1483), NS4 (aa 1888-1925) and NS5 (aa 2332-2423) immunodominant regions, expressed in E. coli, MW 71 kDa. 0.80 mg/mL.
Applications
ELISA, WB, SDS-PAGE, Immunogen, etc.
Formulation
20 mM Phosphate Buffer, pH 7.4.
Purity
> 90% pure by 10% SDS-PAGE.
Storage
Store at 2°C to 8°C short term, -20°C long term. Avoid repeated freeze.
Introduction
Hepatitis C virus (HCV) is a member of the Flaviviridae family, genus hepacivirus. HCV is a small (55-65 nm in size), enveloped, positive-sense single-stranded RNA virus. E1 and E2 are two type 1 transmembrane glycoproteins that are essential components of the envelope. They can assemble as non-covalent heterodimers and are necessary for viral entry and fusion. Hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer (hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans.
Alternative Names
Core protein; HCcAg; HCV core antigen; HCV core protein; Hepatitis C Virus core protein; NS3; NS4; NS5
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.