Recombinant Human B7-H5 Protein (aa 33-194) (Yeast) (VAng-3535Lsx)
Recombinant Human B7-H5 protein, expressed in Yeast. (Uniprot ID: Q9H7M9)
Datasheet
Specifications
Source
Yeast
Target
B7-H5
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
B7-H5, also known as V-domain Ig suppressor of T cell activation (VISTA) is a type I transmembrane protein that functions as an immune checkpoint. VISTA is produced at high levels in tumor-infiltrating lymphocytes, such as myeloid-derived suppressor cells and regulatory T cells, and its blockade with an antibody results in delayed tumor growth in mouse models of melanoma and squamous cell carcinoma.
Alternative Names
B7-H5, SISP1, Gi24, VISTA
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
