Recombinant Human C5 Protein (aa 678-751) (E. coli) (VAng-3853Lsx)

Recombinant Human Complement C5 protein, expressed in E. coli. (Uniprot ID: P01031)

Specifications
Source
E. coli
Target
C5
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
20 mM Tris-HCl based buffer, pH 8.0.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
C5 is a protein that in humans is encoded by C5 gene. It is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is composed of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a C5-convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Alternative Names
Complement C5, C5, CPAMD4
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