Recombinant Human CD177 Protein (aa 22-408) (Mammalian Cells) (VAng-4459Lsx)
Recombinant Human CD177 protein, expressed in Mammalian Cells. (Uniprot ID: Q8N6Q3)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
CD177 is a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis.
Alternative Names
CD177, PRV1, NB1, HNA-2a, NB1 GP
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