Recombinant Human CD19 Protein (aa 20-291) (VAng-4469Lsx)
Recombinant Human CD19 protein, expressed in Cell Free Expression systems. (Uniprot ID: P15391)
Datasheet
Specifications
Source
Cell Free Expression
Target
CD19
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD19 is a transmembrane protein that in humans is encoded by CD19 gene. CD19 is expressed in all B lineage cells, except for plasma cells, and in follicular dendritic cells. CD19 plays two major roles in human B cells. It acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.
Alternative Names
CD19, B4, CVID3, MGC12802
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
