Recombinant Human CD20 Protein (aa 141-188) [TrxA] (VAng-Cr3914)
Recombinant Human CD20 Protein (Ile141-Ser188) fused with a TrxA tag at N-terminus was expressed in E. coli, with a molecular weight of 23.9 kDa. (Accession ID: NP_068769.2)
Datasheet
Specifications
Source
Human
Target
CD20
Type
Tumor Antigens
Applications
ELISA.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Purity
> 85% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R+, CD117+) and progressively increasing in concentration until maturity. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The protein has no known natural ligand and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. It is suspected that it acts as a calcium channel in the cell membrane. CD20 is expressed on all stages of B cell development except the first and last; it is present from late pro-B cells through memory cells, but not on either early pro-B cells or plasma blasts and plasma cells.
Alternative Names
MS4A1; B1; Bp35; CD20; CVID5; LEU-16; MS4A2; S7
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
