Recombinant Human CEACAM5 Protein (aa 1-685) [Fc] (VAng-Cr3942)

Recombinant Human CEACAM5 Protein (Met1-Ala685) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 98.1 kDa. (Accession ID: P06731.3)

Datasheet

Specifications

Source

Human

Target

CEACAM5

Type

Tumor Antigens

Applications

ELISA.

Formulation

Lyophilized from sterile PBS, pH 7.4.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

CEACAM5 is a member of the carcinoembryonic antigen (CEA) family. It plays a role in cell adhesion, intracellular signaling and tumor progression. It mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules. The protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family on chromosome 19. Alternative splicing results in multiple transcript variants.

Alternative Names

CD66e; CEA; carcinoembryonic antigen related cell adhesion molecule 5