Recombinant Human EGFR Protein (aa 1-375) [Fc] (VAng-Cr3973)
Recombinant Human EGFR Protein (Met1-Lys375) fused with a Fc tag at C-terminus was expressed in Baculovirus-Insect Cells, with a molecular weight of 65.1 kDa. (Accession ID: NP_001333870.1)
Datasheet
Specifications
Source
Human
Target
EGFR
Type
Tumor Antigens
Applications
ELISA.
Formulation
Lyophilized from sterile 100 mM Glycine, 10 mM NaCl, pH 7.4.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
EGFR is a transmembrane protein that is a receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands. Deficient signaling of the EGFR and other receptor tyrosine kinases in humans is associated with diseases such as Alzheimer's, while over-expression is associated with the development of a wide variety of tumors. Interruption of EGFR signalling, either by blocking EGFR binding sites on the extracellular domain of the receptor or by inhibiting intracellular tyrosine kinase activity, can prevent the growth of EGFR-expressing tumours and improve the patient's condition.
Alternative Names
ERBB; ERBB1; HER1
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
