Recombinant Human SDF-1 Protein (aa 22-89) [His] (VAng-Cr3952)

Recombinant Human SDF-1 Protein (Lys 22-Lys 89) fused with a His tag at N-terminus was expressed in E. coli. (Accession ID: P48061-2)

Datasheet

Specifications

Source

Human

Target

SDF-1

Type

Tumor Antigens

Applications

ELISA.

Formulation

Lyophilized from sterile PBS, pH 7.4.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

SDF-1 is a chemokine protein in humans. It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The chemokines are characterized by the presence of 4 conserved cysteines that form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, the cysteine residues are adjacent to each other. In the CXC subfamily, they are separated by an intervening amino acid. During embryogenesis, it directs the migration of hematopoietic cells from fetal liver to bone marrow and the formation of large blood vessels. It plays an important role in angiogenesis by recruiting endothelial progenitor cells (EPCs) from the bone marrow through a CXCR4 dependent mechanism

Alternative Names

CXCL12; IRH; PBSF; SCYB12; SDF1; TLSF