Recombinant Human TIMP-1 Protein (aa 24-207) (VAng-Cr4046)

Recombinant Human TIMP-1 Protein (Cys24-Ala207) was expressed in HEK293 Cells, with a molecular weight of 21 kDa. (Accession ID: NP_003245.1)

Datasheet

Specifications

Source

Human

Target

TIMP-1

Type

Tumor Antigens

Applications

ELISA.

Formulation

Lyophilized from sterile 20mM NaAC, 200mM NaCl, pH 5.5.

Purity

> 97% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

TIMP-1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. It is an inhibitory molecule that regulates matrix metalloproteinases (MMPs), and disintegrin-metalloproteinases (ADAMs and ADAMTSs). It plays a regulatory role in the process of implantation, particularly the cytotrophoblast invasion of the uterine endometrium.

Alternative Names

TIMP1; CLGI; EPA; EPO; HCI; TIMP; TIMP metallopeptidase inhibitor 1