Recombinant IKZF3 Protein (Met1-Lys509) [MYC/DDK] (VAng-Cr3792)
Recombinant IKZF3 Protein (Met1-Lys509) fused with a MYC/DDK tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 55.99 kDa. (Uniprot ID: Q9UKT9)
Datasheet
Specifications
Source
Mammalian cells
Target
IKZF3
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
IKZF3 is a protein that in humans is encoded by IKZF3 gene. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
Alternative Names
AIO; AIOLOS; ZNFN1A3; IKAROS family zinc finger 3
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
