Recombinant IL17RA Protein (Met 1-Trp 320) [His] (VAng-Cr3788)
Recombinant IL17RA Protein (Met 1-Trp 320) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 35.2 kDa. (Uniprot ID: Q96F46)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Introduction
IL17RA is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by IL17RA gene (interleukin 17A receptor) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
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