Recombinant IL1B Protein (Ala117-Ser269) [His] (VAng-Cr3765)
Recombinant IL1B Protein (Ala117-Ser269) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 18.29 kDa. (Uniprot ID: P01584)
Datasheet
Specifications
Source
Mammalian cells
Target
IL1B
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
IL1B is a cytokine protein that in humans is encoded by IL1B gene. There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1beta precursor is cleaved by cytosolic caspase 1 (interleukin 1 beta convertase) to form mature IL-1 beta. It is a member of the interleukin 1 family of cytokines. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis.
Alternative Names
IL1F2
Related Product
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