Recombinant IL1RN Protein (Arg26-Glu177) [Fc] (VAng-Cr3766)
Recombinant IL1RN Protein (Arg26-Glu177) fused with a Fc tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 45-55 kDa. (Uniprot ID: P18511)
Datasheet
Specifications
Source
Mammalian cells
Target
IL1RN
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
IL1RN is a protein that in humans is encoded by IL1RN gene. It is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1 beta. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.
Alternative Names
IL1F3; IL1RA
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