Recombinant IL6 Protein (Met1-Met212) [Fc] (VAng-Cr3776)
Recombinant IL6 Protein (Met1-Met212) fused with a Fc tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 55 kDa. (Uniprot ID: P05231)
Datasheet
Specifications
Source
Mammalian cells
Target
IL6
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
IL6 is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. It is capable of crossing the blood-brain barrier and initiating synthesis of PGE2 in the hypothalamus, thereby changing the body's temperature setpoint. It can be secreted by macrophages in response to specific microbial molecules, referred to as pathogen-associated molecular patterns (PAMPs). These PAMPs bind to an important group of detection molecules of the innate immune system, called pattern recognition receptors (PRRs), including Toll-like receptors (TLRs). These are present on the cell surface and intracellular compartments and induce intracellular signaling cascades that give rise to inflammatory cytokine production.
Alternative Names
BSF2; HGF; HSF; IFNB2; IL-6; BSF-2; CDF
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
