Recombinant IL6R Protein (Met1-Pro365) [His] (VAng-Cr3770)

Recombinant IL6R Protein (Met1-Pro365) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 65 kDa. (Uniprot ID: P08887)

Datasheet

Specifications

Source

Mammalian cells

Target

IL6R

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

IL6R is a type I cytokine receptor. It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. The IL6 receptor is a protein complex consisting of an IL-6 receptor subunit (IL6R) and interleukin 6 signal transducer Glycoprotein 130. IL6R also denotes the human gene encoding this subunit. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative Names

CD126; IL-6R-1; IL-6RA; IL6Q; IL6RA