Recombinant ITGB7 Protein (Met1-Leu798) [MYC/DDK] (VAng-Cr3777)
Recombinant ITGB7 Protein (Met1-Leu798) fused with a MYC/DDK tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 87.78 kDa. (Uniprot ID: P26010)
Datasheet
Specifications
Source
Mammalian cells
Target
ITGB7
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
ITGB7 is an integrin protein that in humans is encoded by ITGB7 gene. It is a highly flexible, membrane-bound, extracellular protein that must pair with an alpha subunit for stability. The molecule's flexibility allows it to dynamically regulate its affinity for ligand through conformational changes. Beginning with the apical end of the protein, farthest from the cell membrane, it is composed of a head and upper legs, collectively known as the headpiece, lower legs, a transmembrane domain and a cytoplasmic tail. The top of the head is the I-like domain, sometimes called the betaI domain, which, in combination with the alpha subunit, binds ligand.
Alternative Names
Integrin subunit beta 7
Related Product
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