Recombinant KIR3DL3 Protein (Met1-Leu322) [His] (VAng-Cr3852)
Recombinant KIR3DL3 Protein (Met1-Leu322) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 35-45 kDa. (Uniprot ID: Q8N743)
Datasheet
Specifications
Source
Mammalian cells
Target
KIR3DL3
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
KIR3DL3 is a human protein encoded by KIR3DL3 gene. It is transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. This gene is polymorphic and highly homologous and it can be found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex. It is classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. This protein with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while the protein with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals.
Alternative Names
CD158Z; KIR3DL7; KIRC1
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