ACVR2B (Activin A Receptor Type 2B) is a transmembrane protein, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Diseases associated with ACVR2B include Heterotaxy, Visceral, 4, Autosomal and Right Aortic Arch.