Recombinant Mouse CD177 Protein (aa 193-468) (Baculovirus) (VAng-4462Lsx)
Recombinant Mouse CD177 protein, expressed in Baculovirus. (Uniprot ID: Q8R2S8)
Datasheet
Specifications
Source
Baculovirus
Target
CD177
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD177 is a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis.
Alternative Names
CD177, PRV1, NB1, HNA-2a, NB1 GP
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
