Recombinant Mouse CD33 Protein (aa 1-240) [Fc] (VAng-Cr3927)
Recombinant Mouse CD33 Protein (Met 1-Glu 240) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 51.6 kDa. (Accession ID: Q63994-1)
Datasheet
Specifications
Source
Mouse
Target
CD33
Type
Tumor Antigens
Applications
ELISA.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD33 is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. The extracellular portion of this receptor contains two immunoglobulin domains (one IgV and one IgC2 domain), placing CD33 within the immunoglobulin superfamily. The intracellular portion of CD33 contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that are implicated in inhibition of cellular activity.It is the target of gemtuzumab ozogamicin, an Antibody-drug conjugate for the treatment of patients with acute myeloid leukemia.
Alternative Names
SIGLEC-3; SIGLEC3; p67
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
