Recombinant MSLN Protein (Glu296-Gly580) [His] (VAng-Cr3797)

Recombinant MSLN Protein (Glu296-Gly580) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 31.35 kDa. (Uniprot ID: Q13421)

Datasheet

Specifications

Source

Mammalian cells

Target

MSLN

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

MSLN is a protein that in humans is encoded by MSLN gene. It is a 40 kDa protein that is expressed in mesothelial cells. It is over expressed in several human tumors, including mesothelioma, ovarian cancer, pancreatic adenocarcinoma and cholangiocarcinoma. The interaction between mesothelin and MUC16 (also known as CA125) may facilitate the implantation and peritoneal spread of tumors by cell adhesion. the region of MSLN has 64 amino acids at the N-terminus of cell surface mesothelin.

Alternative Names

MPF; SMRP; mesothelin