Recombinant OX-40L Protein (Gln51-Leu183) [His] (VAng-Cr3832)

Recombinant OX-40L Protein (Gln51-Leu183) fused with a His tag at N-terminus was expressed in Mammalian cells, with a molecular weight of 28-34 kDa. (Uniprot ID: P23510)

Datasheet

Specifications

Source

Mammalian cells

Target

OX-40L

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

Protein lyophilized in sterile PBS/Protein store in sterile PBS.

Purity

> 90% pure by SDS-PAGE.

Storage

Store at -20 °C to -80 °C.

Antigen Information

Introduction

OX40L is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. It is a membrane-bound tumor necrosis family member that is expressed on activated antigen-presenting cells such as B-cell and macrophage. It signals T-cells by binding the OX40 receptor. OX40L has also been designated CD252 (cluster of differentiation 252). Various single nucleotide polymorphisms (SNPs) of the OX40L gene have been identified.

Alternative Names

OX40 ligand