Recombinant PDGFRA Protein (Met1-Glu524) [His] (VAng-Cr3787)
Recombinant PDGFRA Protein (Met1-Glu524) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 90-100 kDa. (Uniprot ID: P16234)
Datasheet
Specifications
Source
Mammalian cells
Target
PDGFRA
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
PDGFRA is a receptor located on the surface of a wide range of cell types. This receptor binds to certain isoforms of platelet-derived growth factors (PDGFs) and thereby becomes active in stimulating cell signaling pathways that elicit responses such as cellular growth and differentiation. The receptor is critical for the development of certain tissues and organs during embryogenesis and for the maintenance of these tissues and organs, particularly hematologic tissues, throughout life. It is related with a typical receptor tyrosine kinase, which is a transmembrane protein consisting of an extracellular ligand binding domain, a transmembrane domain and an intracellular tyrosine kinase domain.
Alternative Names
PDGFRA
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