Recombinant Rhesus CD22 Protein (aa 1-686) [Fc] (VAng-Cr3919)
Recombinant Rhesus CD22 Protein (Met1-Arg686) fused with a Fc tag at C-terminus was expressed in HEK293 Cells, with a molecular weight of 102.1 kDa. (Accession ID: EHH29920.1)
Datasheet
Specifications
Source
Rhesus
Target
CD22
Type
Tumor Antigens
Applications
ELISA.
Formulation
Lyophilized from sterile PBS, pH 7.4.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Antigen Information
Introduction
CD22 is found on the surface of mature B cells and to a lesser extent on some immature B cells. Generally speaking, CD22 is a regulatory molecule that prevents the overactivation of the immune system and the development of autoimmune diseases. CD22 is a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. The presence of Ig domains makes CD22 a member of the immunoglobulin superfamily. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice.
Alternative Names
SIGLEC-2; SIGLEC2; CD22 molecule
Related Product
All of our products can only be used for research purposes. These vaccine ingredients CANNOT be used directly on humans or animals.
