Recombinant TNFSF13B Protein (Ala 134-Leu 285) (VAng-1603Lsx)
Human TNFSF13B is expressed in HEK 293 cells. (Uniprot ID: AAH20674.1)
Applications
SDS-PAGE; WB; ELISA.
Purity
> 95% pure by SDS-PAGE.
Storage
Store at -20°C to -80°C.
Introduction
TNFSF13B is a protein that in humans is encoded by TNFSF13B gene. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. It is expressed as a membrane-bound type II transmembrane protein on various cell types including monocytes, dendritic cells and bone marrow stromal cells. The transmembrane form can be cleaved from the membrane, generating a soluble protein fragment.
Alternative Names
TNFSF13B, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4
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