Human TNFSF13B Protein (Ala 134-Leu 285) [Fc] (VAng-1606Lsx)

Human TNFSF13B, Fc tag, is expressed in HEK 293 cells. (Uniprot ID: AAH20674.1)

Datasheet

Specifications

Source

HEK293 Cells.

Target

TNFSF13B

Type

Tumor Antigens

Applications

SDS-PAGE; WB; ELISA.

Formulation

50 mM Tris, 100 mM Glycine, pH 7.5.

Purity

> 95% pure by SDS-PAGE.

Storage

Store at -20°C to -80°C.

Antigen Information

Introduction

TNFSF13B is a protein that in humans is encoded by TNFSF13B gene. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. It is expressed as a membrane-bound type II transmembrane protein on various cell types including monocytes, dendritic cells and bone marrow stromal cells. The transmembrane form can be cleaved from the membrane, generating a soluble protein fragment.

Alternative Names

TNFSF13B, BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4