Recombinant TNFSF13B Protein (Ala134-Leu285 ) [His] (VAng-Cr3772)
Recombinant TNFSF13B Protein (Ala134-Leu285 ) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 17.97 kDa. (Uniprot ID: Q9Y275)
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Introduction
TNFSF13B is a protein that in humans is encoded by TNFSF13B gene. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. It is expressed as a membrane-bound type II transmembrane protein on various cell types including monocytes, dendritic cells and bone marrow stromal cells. The transmembrane form can be cleaved from the membrane, generating a soluble protein fragment.
Alternative Names
BAFF; BLYS; TALL1; TNFSF20; ZTNF4
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