Recombinant Toxin B Protein (Met1-Leu543) [His] (VAng-Cr3794)
Recombinant Toxin B Protein (Met1-Leu543) fused with a His tag at C-terminus was expressed in Mammalian cells, with a molecular weight of 59.73 kDa. (Uniprot ID: P18177)
Datasheet
Specifications
Source
Mammalian cells
Target
Toxin B
Type
Tumor Antigens
Applications
SDS-PAGE; WB; ELISA.
Formulation
Protein lyophilized in sterile PBS/Protein store in sterile PBS.
Purity
> 90% pure by SDS-PAGE.
Storage
Store at -20 °C to -80 °C.
Antigen Information
Introduction
Toxin B is a toxin produced by the bacteria. the bacteria can produce two major kinds of toxins that are very potent and lethal; an enterotoxin (Toxin A) and a cytotoxin (Toxin B, this protein). It is a cytotoxin that has a molecular weight of 270 kDa and an isoelectric point. Toxin B has four different structural domains: catalytic, cysteine protease, translocation, and receptor binding. The N-terminal glucosyltransferase catalytic domain includes amino acid residues 1–544 while the cysteine protease domain includes residues 545–801. The glycosylation activity of toxin B occurs in the N-terminal catalytic region (residues 1–544). This region glycosylates substrates independent of any cytotoxic activity.
Alternative Names
tcdB
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